Professional Information CEO, AUTOTAC Bio Inc., Seoul KoreaProfessor, Seoul National University College of Medicine Inside Job: Antibody Flags Toxic Tau for Disposal by Lysosome 24 Apr 2026 ...
Tau immunotherapy has been hindered by poor antibody access across the blood-brain barrier and weak binding to target epitopes. The trial failures of many full-length antibodies against various ...
As the resident immune cells of the brain, microglia occupy its every gyrus and sulcus, where they stand ready to contain threats and make repairs. Scientists have discovered that this contingent is ...
White-matter hyperintensities, a sign of damage to the brain’s vasculature, are common on MRI scans of people with Alzheimer’s disease. Do they indicate an independent vascular co-pathology, or are ...
18 – 22 April 2026 DOWNLOAD TO YOUR CALENDAR Saint Charles, Missouri View Conference Website ...
At last year’s AD/PD meeting in Vienna, what is now the Consortium for Biomedical Research and AI in Neurodegeneration was an idea. By this year’s AD/PD in Copenhagen, C-BRAIN had become an operating ...
Once more than 4 percent of tau molecules in a person’s blood are phosphorylated at residue 217, the clock starts ticking—toward the first symptoms of Alzheimer’s disease, that is. How long it might ...
Post-marketing data chart immunotherapy performance in early-onset Alzheimer’s. The antibodies lowered amyloid and slowed functional decline. However, tangles continued to form. “These results offer ...
The world did not end today as predicted, but unfortunately we have to report that development of another potential drug did. Allon Therapeutics Inc. announced 19 December that its drug candidate ...
Transferrin-receptor shuttles distribute antibody cargo throughout the parenchyma, steering clear of ARIA-provoking vascular amyloid. Trontinemab is enrolling Phase 3 for early AD, announces plans for ...
Because hypertension is linked to a greater risk of dementia, several trials have investigated whether lowering blood pressure in older people would protect the brain. Data from cohorts of a few ...
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