The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

San Francisco 49ers running back Christian McCaffrey won't return in Week 6, but will likely make his long-awaited comeback ...

Two weeks after blowing a 24-14 lead in the fourth quarter to the Los Angeles Rams, the Niners (2-3) did it again Sunday.

SANTA CLARA—The West Coast heatwave wreaked havoc on the 49ers’ practice schedule this past week, leading coach Kyle Shanahan ...

The San Francisco 49ers (2-2) meet a fellow NFC West foe when they host the Arizona Cardinals (1-3) on Sunday, October 6, ...

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

The record-breaking heat at Levi's Stadium on Sunday sent San Francisco 49ers fans to the concourses to watch the game on ...

San Francisco 49ers linebacker Dre Greenlaw shoved a Cardinals player in a sideline skirmish during Sunday's game, likely ...