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BNT162b2 vaccine against Covid-19 is composed of an RNA having 4284 nucleotides , divided into 6 sections , which bring the information to create a factory of S Spike proteins , the ones used by ...

Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors.

Most of our knowledge on microbial physiology and biochemistry is based on studies performed under laboratory conditions. For growing hydrogen-oxidizing anaerobic, autotrophic prokaryotes, an H 2:CO 2 ...

Authors Ramezani-Rad P 1, 2 Cottrell CA 2 Marina-Zárate E 1, 2 Liguori A 2 Landais E 2 Myers A 1, 2 Lee JH 2 Baboo S 2 Flynn C 2 McKenney K 2 Salcedo E 2 Zhou X 2 Kalyuzhniy O 2 Georgeson E 2 Phelps N ...

To survive in the tumour microenvironment, cancer cells undergo rapid metabolic reprograming and adaptability. One of the key characteristics of cancer is increased glycolytic selectivity and ...

Antibiotics are widely used in humans and animals, but there is a big concern about their negative impacts on ecosystem and human health after use. So far there is a lack of information on emission ...

Currently, ~95% of patients with testicular germ cell tumour (TGCT) are cured, resulting in an increasing number of TGCT survivors. Although cured, these men face potential late adverse effects and ...

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Excessive systemic inflammation is characteristic to various acute conditions including sepsis, viral infections and immunotherapy-induced adverse events such as cytokine release syndrome (CRS).

The PIN-FORMED (PIN) protein family of auxin transporters mediates polar auxin transport and has crucial roles in plant growth and development 1,2. Here we present cryo-electron microscopy structures ...

A network pharmacology method was implemented using drug and disease databases to target QKL and cholestasis hepatitis, respectively. The functional protein association network STRING database was ...