Brock Purdy had two costly interceptions against the Cardinals, resulting in a disappointing one-point loss for the 49ers.

San Francisco 49ers running back Christian McCaffrey won't return in Week 6, but will likely make his long-awaited comeback ...

No lead is ever safe for the 49ers after they wasted another double-digit lead to lose 24-23 to the Cardinals.

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

Tom Brady awards Arizona Cardinals QB Kyler Murray with the LFG Player of the Game after his dominant performance against the ...

San Francisco 49ers linebacker Dre Greenlaw shoved a Cardinals player in a sideline skirmish during Sunday's game, likely ...

Another week, another full slate of NFL action nearly in the books. And Week 5 has had no shortage of drama up to this point, ...

One week after coming up short in their comeback attempt against the undefeated Minnesota Vikings, the Green Bay Packers ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Watch San Francisco 49ers quarterback Brock Purdy's best plays vs. the Arizona Cardinals in the Week 5 matchup.

Watch Los Angeles Rams running back Kyren Williams' best runs from his 102-yard game vs. the Green Bay Packers in Week 5 of ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...