Scientists are trying to parse the cellular interactions that foment ARIA during amyloid immunotherapy. At last month’s AD/PD conference in Copenhagen, Denmark, speakers highlighted the role of both ...
Scientists are getting closer to figuring out how amyloid immunotherapy causes ARIA, and perhaps how to prevent it. At last month’s AD/PD conference in Copenhagen, Denmark, the spotlight was on innate ...
Interconnected networks of neurons—i.e., circuits—are the basis of brain function, and astrocytes support synapses within them. They also form networks of their own, passing messages and sharing ...
CAR-T cell therapy has practically become a household name, given its success in taking down blood cancers. The chimeric antigen receptors used in this type of cell therapy are designed to sic killer ...
Professional Information CEO, AUTOTAC Bio Inc., Seoul KoreaProfessor, Seoul National University College of Medicine Inside Job: Antibody Flags Toxic Tau for Disposal by Lysosome 24 Apr 2026 ...
Bifidobacterium breve A1 is a proprietary strain of probiotic bacteria isolated from the intestinal tract of an infant. A main component of the human gut microbiome, Bifidobacteria species form part ...
Tau immunotherapy has been hindered by poor antibody access across the blood-brain barrier and weak binding to target epitopes. The trial failures of many full-length antibodies against various ...
Early onset familial Alzheimer disease (eFAD) is hereditary and marked by Alzheimer disease symptoms that appear at an unusually early age. Symptoms can start in a person's thirties, forties, and ...
This database provides information about selected rodent models of neurodegenerative disease, including Alzheimer’s, Parkinson’s, and ALS. By summarizing, visualizing, and continuously updating ...
In 2009, Robert Baloh and colleagues reported a transgenic mouse model of ALS based on the overexpression of mutant TARDBP (TDP-43) (Wegorzewska et al., 2009). These mice developed several features of ...
As post-translational modifications go, phosphorylation has topped the charts of late, with a handful of different p-tau’s emerging as valuable markers for Alzheimer’s disease and even peripheral ...
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