Arizona, San Diego and the Padres
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Here's how to watch Saturday's Arizona Diamondbacks vs San Diego Padres game, including start times, TV channels, scores and how to stream.
Who won the Arizona Diamondbacks vs. San Diego Padres game in the 2026 MLB World Tour: Mexico City Series? Get the final score, highlights, and a summary of the historic clash in Mexico City. Check the results now to see which team dominated the field in this international MLB showdown.
The San Diego Padres defeated the Arizona Diamondbacks by a final score of 6-4 in the first game of the Mexico City Series on Saturday. Mason Miller earned his league leading 10th save in the 9th inning.
The Padres' record-tying run of four-run-plus comebacks ended in Mexico City as they lost 12-7 to the Diamondbacks after a bullpen meltdown.
Tim Tawa hit a grand slam to highlight Arizona's six-run seventh inning, Ildemaro Vargas homered to extend his hitting streak to 23 games and the Diamondbacks rallied to defeat the San Diego Padres 12-7 and split the two-game series at Alfredo Harp Helú Stadium.
BOTTOM LINE: The Arizona Diamondbacks host the San Diego Padres to begin a two-game series. Arizona has a 14-11 record overall and an 8-5 record at home. The Diamondbacks are 10-2 in games when they scored five or more runs.
The San Diego Padres' lineup, pitching matchups and how to watch Saturday's game against the Arizona Diamondbacks.
See all the player props bets with current odds for the MLB matchup between the Arizona Diamondbacks and Padres on Saturday, April 25, 2026.