Although prostate cancer initially responds and regresses in response to androgen-depletion therapy, most human prostate cancers will re-grow as an androgen-independent tumour. The goal of our study ...

Gene amplification is one of the major mechanisms of oncogene activation in tumorigenesis. Currently, however, direct identification of amplified genes in cancer remains difficult. The most important ...

Researchers at the National Institute on Aging will distribute a recently established mouse cDNA microarray/clone set containing 7,407 unique genes to 20 designated academic centers worldwide. The new ...

Current microarray analysis uses 'chips' containing either 25-residue oligonucleotides synthesized by photolithography or cDNAs placed by robotic spotting. In the April Nature Biotechnology, Hughes et ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.

In those days, there were a limited number of known genes to select from. "The first thing you want is genes that have a name and activity associated with them, because if one of those is indicated as ...

What is an RNA sequencing library? In all RNA-seq experiments, a library of cDNA fragments attached to adapters must be synthesized in order for sequencing to be successful. How do you prepare an RNA ...