Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, ...

Researchers have identified how to encourage tumors to build their own immune hubs—structures that look and function like lymph nodes—deep in the middle of cancer. Such immune hubs, known as tertiary ...

Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity. Hydrogen sulfide (H2S) treatment restored chromatin interactions and ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion ...

CAR T-cell therapy was first developed as a lymphoma treatment but has recently been applied to autoimmune diseases, primarily lupus, systemic sclerosis, and myositis. Up to this point, ulcerative ...

Blood cancers such as leukemia, lymphoma, and myeloma often begin in the bone marrow and disrupt normal blood cell formation.

The U.S. Food and Drug Administration (FDA) has granted fast track designation to UB-VV111 for the treatment of ...