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2025 Week 4 NFL picks, odds, best bets from proven model

NFL longshot picks, 2025 Week 4 odds, player props: This parlay could bring an $8,000 return on $10 bet

The Week 4 NFL schedule features a compelling slate of matchups across the league.

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SportsLine · 4h

NFL Week 4 odds, score predictions: SportsLine computer simulation model reveals picks for every game on the football schedule

NFL Week 4 predictions: ESPN matchup predictor's picks, win probabilities for this week

NFL Week 4 picks, predictions: Who will win pivotal games this week?

The Bills have one of the NFL's best offenses.

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Here’s how to watch Lions vs. Ravens live for free on Monday Night Football

NFL Week 3 betting recap, trends, line movement: Texans flailing, Bills a massive favorite