Early results from preclinical studies and a clinical trial led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center and Stanford Medicine suggest that combining targeted radiation ...

Sarcoma is a rare, complex cancer with over 150 subtypes, each requiring different treatments. Care at specialized centers ...

Real-world outcomes of biomarker-intended pembrolizumab use in soft tissue sarcomas. Phase 3, multicenter, randomized, controlled open-label study: Efficacy and safety of M701 (EpCAM×CD3 bispecific ...

According to new research, radiation therapy administered before surgery rarely produces favorable responses in patients with retroperitoneal sarcoma (RPS), a rare and aggressive cancer that forms in ...

Ewing sarcoma is a rare, aggressive cancer that primarily strikes children and adolescents, yet it can present in infants, where it is exceptionally uncommon. U.S. registry data show an incidence of ...

Sarcomas are aggressive, immunologically cold tumors with limited benefit from immune-checkpoint blockade (ICB). Through integrated multi-omics, functional, and clinical analyses, we identify pyruvate ...

Pre-clinical data demonstrated anti-tumour effect in Ewing sarcoma (ES) for zoledronic acid. This provided the rationale for the second randomisation (R2) in the EURO EWING 2012 (EE2012) trial, ...

Transitioning from accelerated to traditional status, the FDA's decision expands eligibility for the first solid-tumor engineered T cell therapy to include adolescents aged 12 and older.

After enrolling in a clinical trial for a rare soft tissue sarcoma, Andi Straus is doing well and enjoying life, including hiking with her son, Nadav, in Vail, Colorado. Abemaciclib kept the cancer ...

There was a powerful show of support at North Park on Saturday morning during a walk that brings together people impacted by a rare form of cancer.

“This was difficult information to hear, and it was not sugar- coated,” said Gracie Butler, who was told she had spindle cell sarcoma Vanessa Etienne is a Staff Writer for PEOPLE on the Health team.

Only one retroperitoneal sarcoma (RPS) patient out of 22 achieved meaningful tumor shrinkage with pre-surgical radiation, while over 75% of the sample saw no significant change and 18% experienced ...