As Chief Editor of one of the two journals in which Biopharma Dealmakers appears, I have a keen interest in the process of translating biomedical research into new drugs, including the partnerships ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

Since the first description of oncogenes over 25 years ago (Stehelin et al., 1976), there has been tremendous progress in our understanding of the roles different genes play in the oncogenesis process ...

First patients dosed in LAUNCH ALS, an investigator-initiated trial in China conducted in partnership with Tenacia Biopharmaceutical, to support accelerated global clinical development strategy ...

Oligonucleotides—short, synthetic nucleotide strands that can be used as drugs to modulate gene expression—were at the heart of two deals inked in December. Vertex Pharmaceuticals will pay Entrada ...

Oligonucleotides are short strands of DNA or RNA that play a major role in drug discovery and molecular diagnostic chip technology. They are used from initial research and screening through to target ...

Residual amount of phosphodiester from incomplete sulfurization and side reaction. A review by Goodchild eloquently summarizes the established technique for oligonucleotide synthesis which has been ...

Oligonucleotide-based drugs continue to flow into developmental pipelines, and the relatively large numbers now being tested in humans and progressing through late-stage clinical studies have buoyed ...

Peptides and oligonucleotides, often grouped together as TIDES, are increasingly seen as powerful therapeutic tools. 2 Their high specificity, tunable biological activity, and ability to modulate ...

SOUTH SAN FRANCISCO, Calif., June 22, 2026--(BUSINESS WIRE)--Trace Neuroscience, Inc., a biopharmaceutical company expanding the promise of genomic medicine for people living with neurodegenerative ...