Dysregulated neuronal excitability is a major feature of many neurological and psychiatric conditions. The Kv7 potassium channel has an important role in regulating neuronal firing, making it a ...

A growing body of neuroscience research is converging on a counterintuitive idea: the disorderly brain activity triggered by LSD might actually work against the hyper-synchronized neural firing that ...

(from left) Prof. Florian Mormann and Dr. Stefanie Liebe revise an established theory of stimulus processing in nerve cells during memory processing. How does the brain retain a sequence of events in ...

Using optogenetics, researchers used pulses of light to prevent seizure-like activity in neurons. This is the first use of optogenetics to modulate seizure activity at the network level in human brain ...

During an epileptic seizure, pyruvate levels in astrocytes increased, while ATP levels in neurons decreased. The experiments suggest that the transfer of metabolic energy molecule transfer may be ...

The study sought to evaluate the efficacy, safety, and tolerability of azetukalner, administered as an oral, adjunctive, once ...

Neuronal degeneration is the most severe long-term consequence of repetitive seizures in patients with epilepsy, which until now was thought to be primarily caused by excitotoxicity, or ...

Investigators led by Northwestern Medicine scientists have identified mutations in a gene coding for a key ion channel in the ...

The acquisition helps diversify UCB’s small molecule-centric arsenal of seizure treatments with a potentially one-off therapy ...

Severe liver injury cases prompt required liver function testing for patients taking the epilepsy drug as adjunctive therapy for focal seizures.