Although N-linked glycans play pivotal roles in the regulation of antibody effector functions, little is known about the composition and functional impact of glycans attached to human B cell receptors ...
However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...
The E3 ubiquitin ligase Casitas B-lineage lymphoma (CBL) promotes positive selection and antigen responses in mouse T lymphocytes by ubiquitinating ZAP70. Conversely, mouse CBL and CBL-B mutually ...
Singapore has one of the highest life expectancies in the world, yet many individuals spend almost a decade in poor health toward the end of life. Scientists from the Yong Loo Lin School of Medicine, ...
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the ...
Conjugate vaccines are composed of bacterial polysaccharide antigens covalently linked to protein carriers, enabling T cell-dependent immune responses that induce high-affinity antibodies and ...
T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...
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