The transport cycle of TRAP transporters is depicted schematically in the middle of the figure. To trap the transporter in specific states, the stator and elevator domains were cross-linked by ...

The study of peptide transport mechanisms and membrane proteins has gained considerable momentum as researchers unravel the molecular intricacies underlying nutrient uptake, intracellular signalling ...

Pi plays crucial metabolic and structural roles in living organisms. It is essential for bioenergetics (ATP, GTP), metabolic regulation through glycolysis and oxidative phosphorylation, intercellular ...

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial ...

Using cryo-EM structure determination, molecular dynamics simulations, and electrophysiological analyses, researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences ...

Researchers meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings revealed that during sporulation, ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...