Nuclera, the biotechnology company enabling rapid access to high-quality proteins and leadXpro, a specialist in structure-based drug discovery for membrane proteins, today announced a scientific ...

Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...

Membrane proteins are integral to cellular function, mediating processes from signal transduction to transport. Research in this domain has long been challenged by the inherent instability of these ...

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

Cambridge biotech Nuclera and Swiss company leadXpro have joined forces in a bid to fast-track membrane protein programmes.

Membrane proteins are key targets for therapeutic intervention using antibody biologics. Over 60% of FDA-approved drugs act on these proteins. Studying them is challenging because the proteins must be ...

Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their structures in a natural membrane environment is crucial for enhancing our ...

Ion channels are narrow passageways that play a pivotal role in many biological processes. To model how ions move through ...

Researchers discover that hearing-essential proteins (TMC1/TMC2) also regulate cell membranes, and their malfunction is a primary cause of permanent hearing loss.

Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...