RNA silencing in fungi encompasses a collection of post-transcriptional and transcriptional pathways that regulate gene expression, maintain genome integrity and defend against invasive nucleic acids.

Gene silencing refers to any mechanism that turns down or switches off the expression of a specific gene so that less of its protein, or none at all, is produced. Crucially, the gene's DNA is left ...

Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers. RNA interference (RNAi) ...

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from ...

Plain-language definition: RNA therapy is medicine that works by adding, blocking, or changing RNA instructions inside cells. More formally, it is a class of treatment that uses RNA molecules, or ...

Gene knockdown is a common method for studying gene function by reducing messenger ribonucleic acid (mRNA) levels without altering the deoxyribonucleic acid (DNA). Among the available techniques, RNA ...