Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

Twenty years ago, the protein complex cohesin was first described by researchers at the IMP. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped ...

Temporarily disabling a protein complex that organizes DNA into loops inside the cell's nucleus drastically disrupted the three-dimensional structure of the genome, but surprisingly most genes ...

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermatogonial stem cells (SSCs), the stem cells ...

A cohesin molecule ensures the proper distribution of DNA during cell division. Scientists can now demonstrate the concept of its carabiner-like function by visualizing for the first time the open ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...

Best known for its ability to regulate the separation of sister chromatids during cell division, the cohesin protein complex, a ring-shaped structure, has shown that it has other powers, such as the ...

Aging is characterized by increases in inflammation and decreases in stem cell function. The relationship between these processes remains incompletely understood. Researchers of the Leibniz Institute ...

Racial differences in treatment decision-making patterns and decisional regret in patients with localized prostate cancer. This is an ASCO Meeting Abstract from the 2016 Genitourinary Cancers ...

Twenty years ago, the protein complex cohesin was first described by researchers. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped structure of ...