-- Updated data from Phase 1/2 trial in end-stage metastatic MSS-CRC further support the association of circulating tumor DNA (ctDNA) reduction with extended overall survival -- -- GRANITE has ...
-- Early progression-free survival (PFS) trends favor GRANITE recipients with hazard ratios of 0.82 in the overall population ([95% CI, 0.34-1.67]; 62% censored) and 0.52 (48% relative risk reduction ...
Muzastotug (ADG126) shows a promising 33% overall response rate in its Phase 2 dose expansion study for MSS CRC, indicating potential effectiveness in treating this cancer subtype. The SAFEbody ...
Confirmed response rates in expansion cohorts of 32% at 10 mg/kg Q3W dose and 20% at 8.6 mg/kg Q3W -- Estimated progression free survival of ...