Most of the patients with CGD present during the first 5 years of life. The most commonly involved organs are: skin, lungs, GI tract, lymph nodes, liver, and spleen. An early onset of severe recurrent ...

Chronic granulomatous disease (CGD) describes an inherited genetic condition that affects a person’s immune system. It results in a type of immunodeficiency and causes people to be highly susceptible ...

A peritonsillar abscess forms in the tissues of the throat next to one of the tonsils. An abscess is a collection of pus that forms near an area of infected skin or other soft tissue. The abscess can ...

An abscess occurs when an infection causes a pocket of pus to develop. Abscesses can develop on the skin, in the mouth, or inside the body. Bacterial infections typically cause abscesses. Pus develops ...

A skin abscess is a bump within or below the skin’s surface. It is usually full of pus, painful, and may feel thick and swollen. This is typically caused by a bacterial infection. A skin abscess may ...

A gene therapy that modifies a patient’s own stem cells has shown promise against X-linked chronic granulomatous disease (X-CGD), the most common form of CGD, a hereditary immune disorder. Of the nine ...

NADPH oxidase is the key enzyme for the inducible production of superoxide (O − 2) and superoxide-derived reactive oxygen species in phagocytes and plays a crucial role in host defence mechanisms ...

Chronic granulomatous disease (CGD) is a rare genetic immunodeficiency associated with phagocyte function. It was first described in the 1950s. It is caused due to functional impairment in the NADPH ...