B cells are a crucial component of immunity, but their function, especially antibody secretion, has largely been studied in the context of secondary lymphoid organs (SLOs) and systemic immune ...

Immune responses and self-tolerance are critical in maintaining systemic and tissue homeostasis. Autoimmune disease results from uncontrolled immune responses against self-antigens, whereas cancer ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific infections, remember them, and mount a targeted response by producing ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of ...

Sjögren’s disease (SjD) is a chronic, multisystem autoimmune disorder characterised by lymphocytic infiltration of exocrine ...

When people think about health, they often focus on specific organs like the heart or brain. But many changes related to chronic conditions or ageing begin in the smallest units of your body — your ...